New York state Health Commissioner Mary Bassett has announced she will resign at the end of the year.

"I am leaving now so the next commissioner can have the chance to lead this great department for a full four-year term under the leadership of Gov. Hochul," Bassett wrote in a statement.

Bassett, also a former New York City health commissioner, says she'll return to Harvard T.H. Chan School of Public Health.

Under her tenure as state health commissioner in the last year, she's dealt with a COVID resurgence as well as polio and monkeypox outbreaks.

Hochul says she is “deeply grateful” to her.

"She has worked tirelessly to keep New Yorkers informed, healthy and safe," said Hochul in a statement.

Bassett will step down on Jan. 1, 2023.