Council member Charles Barron, and other leaders gathered at the corner of Essex Street and New Lots Avenue, the intersection where the accident happened.
Police say a Chevy Impala rear-ended a van, which then struck a Ford Escape. They say the Impala then hit an MTA bus.
The intersection has three lanes of traffic, four crosswalks and two bike lanes. There are only stop signs to help ensure everyone gets across safely.
Also fighting for change were members of Community Board 5, Man Up, Operation of Power and Nation of Islam.
Barron says residents have been complaining about safety issues at the intersection, but nothing has changed.
Department of Transportation officials say they have installed an all-way stop at the intersection and have begun a study to see if a light is needed.